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Xeroderma Pigmentosum Mnemonic for USMLE
Xeroderma pigmentosum is a genetic defect caused by a mutation in nucleotide excision repair, which is the DNA repair process used to remove thymine dimers caused by UV light exposure. Thymine dimers are large, bulky lesions, and their presence leads to distortions in the DNA helix. These thymine dimers then may interfere with normal ...
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