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Randomization
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Howie
Mandel
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Randomization
in Clinical Trials
Survival
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Insulin-Resistance
NAFLD
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Jonathan
Beauchamp
Mendelian Randomization
Tutorial
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Sclerosis
Randomized
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Mendelian
Genetics
52:59
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the Causal Inference Interest Group (CIIG)
George Davey Smith | Mendelian Randomization - what it was, what it is, and what it should become
Mendelian randomization (MR) is an approach that uses the special properties of germline genetic variation to help establish how an exposure phenotype influences an outcome phenotype. The recent exponential growth in the use of MR reflects the rapid expansion in data that are available for conducting such studies. This talk will introduce the ...
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Sarah McKay PhD Neuroscientist on Instagram: "If oestrogen was the main driver of women’s brain health, this study would have found it. It looks intimidating, but the question is pretty simple: do lifelong tendencies toward higher or lower oestrogen exposure cause differences in brain ageing, depression or Alzheimer’s risk? TLDR: No Researchers used Mendelian randomisation (genes as a natural experiment) to avoid confounding & reverse causation issues. Across the biobank datasets & multiple horm
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