Memes on Instagram: "once the hanger leaves, i’m a whole new person 😎 Hunger can cause irritability because the body relies on a steady supply of glucose to regulate brain function and mood. When blood sugar drops, the brain triggers the release of stress hormones like cortisol and adrenaline, which can make a person more reactive or easily frustrated. At the same time, low energy levels reduce the brain’s ability to manage emotional responses, leading to shorter tempers and decreased patience.