This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as its history from the comparative analysis of the first amino acid sequences ...

Analysis of Roche KAPA Target Enrichment kit experimental data obtained on an Illumina sequencing system is most frequently performed using a variety of publicly available, open-source analysis tools.

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

In recent years, providing authentic and unique research experiences for undergraduates has become increasingly important, yet many educational institutions struggle to provide their students with ...

By adapting techniques originally used to study ancient DNA from archaeological specimens, researchers at the University of Chicago were able to recover genetic information from nearly century-old ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis ...

DNA sequence analysis software needn't be expensive. For a decade, molecular biologist Kjeld Olesen has spent much of his spare time developing pDRAW32, a free sequence-analysis software package for ...

GenAI models have revolutionized bioinformatics applications by learning from massive biological datasets, genomic sequences, protein structures, and single-cell transcriptomes, without requiring ...