One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the ...

Maintenance of genome integrity is vital for cells and organisms. Cells have evolved a prompt set of actions, the DNA damage response (DDR), to react to any discontinuity in their nuclear DNA. DNA ...

Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the ...

The human genome is made up of ~3 billion letters of DNA and at each position it is possible to have different letters, called variants. Some variants are harmless but others can be detrimental, ...