Lipids formulated with a bioreducible linker form the wall of nanoparticles encapsulating the mRNA of Cas9 plus sgRNA. Upon entering the cell, in vitro or in vivo, the linkers are broken and the ...

New research found that mRNA vaccines for COVID-19 could enhance cancer treatments and help patients live longer.

Two pioneering scientists who created the technology behind life-saving Covid-19 vaccines have won the Nobel Prize in medicine or physiology. Dr. Katalin Karikó and Dr. Drew Weissman, both of the ...

During translation, messenger RNA guides protein production, and certain conditions can favour particular proteins. Helicase enzymes and mRNA structure control translation during defence responses in ...

Biochemist Katalin Karikó and immunologist Drew Weissman won the Nobel Prize in Physiology or Medicine Monday for their foundational research showing that chemical modifications to the molecular ...

Marissa Russo is a former STAT intern supported by the AAAS Mass Media Science & Engineering Fellowship. An oral capsule can efficiently deliver liquid mRNA therapy directly to the gut, a possible new ...