Our study profiled the dynamic epigenomic landscape, annotated regulatory DNA elements, and identified and validated BCL6B as ...

Stem cells possess the unique abilities of self-renewal and differentiation into various cell types, making them highly ...

Rapid precision run-on sequencing (rPRO-seq) may help doctors understand disease states and treatment response in real time. Researchers at Sylvester Comprehensive Cancer Center (FL, USA) have ...

Recently, the research team led by Professor Ling Shuai from the State Key Laboratory of Medicinal Chemical Biology at Nankai ...

An iron-sensing tool lets researchers watch stem cells transition in real time, linking iron dynamics to the earliest decisions in cells. Study: The genetically encoded biosensor FEOX is a molecular ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Enhancers play a crucial role in directing gene expression programs essential for cellular differentiation and development. Recent advancements in 3D genome ...

Effect of intrinsic STING of CD8+T cells on self-metabolic reprogramming and anti-tumor effects. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a ...

The use of induced pluripotent stem cells (iPSCs) has led to a paradigm shift in cellular immunotherapy. By reprogramming somatic cells into a pluripotent state, iPSCs represent a renewable source of ...

Given troves of data about genes and cells, A.I. models have made some surprising discoveries. What could they teach us someday? Credit...Doug Chayka Supported by By Carl Zimmer In 1889, a French ...