The shikimate pathway is fundamental for the biosynthesis of aromatic amino acids—tryptophan, tyrosine and phenylalanine—in plants, bacteria and fungi. This pathway, which is absent in mammals, has ...

Haemoglobin is a paradigm for exploring allosteric regulation, wherein ligand binding at one site induces conformational changes that affect functional activity at a distant site. These structural ...

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...