Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

Researchers have reported a chip-scale microoptical system that enables continuous, real-time fluorescence monitoring of three-dimensional living microtissues, addressing a longstanding barrier ...

A multimodal imaging study combines cryo-X-ray nanotomography and super-resolution fluorescence microscopy to reveal how protein-coated nanoparticles behave in cells. (Nanowerk Spotlight) The ...

Researchers use directed evolution to create magneto-sensitive fluorescent proteins that can interact with magnetic fields and radio waves ...

Processes in the human body are shaped by the interaction of various biomolecules, such as proteins and DNA. These processes take place in a range of often just a few nanometers. They can therefore no ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...

The mIRage-LS optical photothermal infrared (O-PTIR) microscope has a spectral range of 3600-2700 and 1800-800 cm-1 for infrared (IR) spectroscopy and a spectral range of 3900 – 200 cm-1 for Raman ...

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue ...