Hematopoietic stem cell transplantation is becoming an increasingly important approach to treatment of different malignant and non-malignant disorders. There is thus growing demand for diagnostic ...

Forensic DNA analysis can provide conclusive evidence to trace specific individuals to a crime scene and has been instrumental in solving cold cases, exonerating the wrongfully accused and bringing ...

DNA varies between and within species, and so it can be used in forensic work when biological material is associated with a crime or other legal case. Forensic DNA analysis began in 1985 with the ...

Imagine you’re studying colon cancer using a colon cell line model. After three painstaking years of research, your first major publication describes several new findings on the molecular pathways in ...

A high number of forensic laboratories presently use PCR and capillary electrophoresis (CE)-based techniques to investigate short tandem repeat (STR) markers and alternative polymorphisms. Sequencing ...

Frequently the only biological material available to identify persons is DNA in a very degraded state. In these cases, the kits usually employed to carry out DNA identifications do not produce ...

Multiplex PCR is a difficult technique that allows amplification of two or more products in parallel in a single reaction tube. This technology was first described by Chamberlain et al., in 1988, and ...

In this interview, News Med is talking to Gabriela Saldanha about DNA Fragmentation and Sanger Sequencing. What are Sanger sequencing and DNA-fragment analysis? Where are these analyses used? Sanger ...

The latest forensic weapon is a device that identifies crime scene DNA in a few hours. A new portable DNA analyzer performs real-time analysis of blood samples left at the scene of a crime.