Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

Researchers have defined a new genetic disease caused by a mutation in the IVNS1ABP gene. The condition marks a rare ...

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...

Researchers have engineered a dual-targeting nanocarrier that safely sneaks potent chemotherapy past the blood-brain barrier.

Brain fog can be scary. It might appear innocently, like losing your car keys or forgetting what date you scheduled that appointment on. Some of this memory loss is normal—it’s just a natural side ...

As cell therapy advances toward clinical reality, iPSC-derived cellular products, in vivo reprogramming strategies, and ...

The human brain has 86 billion neurons connected by roughly 100 trillion synapses, making it one of the most complex objects in the known universe. Each year neuroscientists make fascinating, ...