Study of the bleeding tendency in uremia in 26 subjects, 10 of whom were bleeding, showed platelet counts and plasma coagulation factors to be normal. There was a significant inverse correlation ...

Platelet functionality analysis could pave the way to improving drug asset selection and de-risking clinical trials ...

Scientists have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which makes blood-vessel walls ...

A new study successfully identifies new genetic variants involved in the formation of platelets and more importantly, defines how genes near these variants affect platelet size and number using a ...

Outcomes With Local Therapy and Tyrosine Kinase Inhibition in Patients With ALK/ROS1/RET-Rearranged Lung Cancers Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8% ...

Platelet function may aid in determining disease severity for patients with psoriasis who are at an increased risk of developing cardiovascular disease (CVD) and increased inflammation, a review notes ...

THE term primary or "spontaneous" hemostasis refers to a complex series of biologic events occurring in immediate response to blood-vessel severance or injury. Although damaged or cut blood vessels ...

Platelets, or thrombocytes, are small, colorless cell fragments in the blood that are responsible for the process of clotting the bleeds. Whenever a blood vessel gets damaged, it sends a signal to the ...

Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...

Scientists at Uppsala University have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which ...