Pulmonary arterial hypertension (PAH) is a rare condition that's difficult to treat. The hallmarks of the disease—narrowing of the arterioles and capillaries that deliver blood to the lungs—force the ...

To determine the effects of pericytes and angiopoietin-1 on the expression of occludin and zonula occludens-1 (ZO-1) in retinal endothelial cells (ECs) under both normoxic and hypoxic conditions.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, No. 51 (December 21, 2010), pp. 22290-22295 (6 pages) Modern functional imaging techniques of the brain ...

Depending on whom you ask, pericytes are either vital vascular regulators that boost blood flow to needy areas of the brain, or mere bystanders that let other cells take on that job. A new study ...

A recent study reveals that SARS-CoV-2 may damage blood vessels without infecting cells directly. A recent study reveals the details of how SARS-CoV-2 affects pericytes, a cell type critical for the ...

Of all the body’s organs, the brain is the most like Area 51: Entry to the region is severely restricted, thanks to a barricade of cells and molecules known collectively as the blood-brain barrier.

Pericytes are a type of cells found in the brain's blood vessels. Using advanced imaging technique, it was found that these cells grow even in the empty spaces when the pericytes die, reveals a new ...

Researchers have built a 3D human blood-brain barrier in the lab and discovered a key role of brain pericytes in cerebral malaria disease Subscribe to ...

Research sheds new light on how a breakdown in the brain's vascular system predates the accumulation of toxic plaques and tangles in the brain that bring about Alzheimer's disease. The research ...

Inside the eye, at the interface between blood vessels and the retina, lies a boundary that prevents harmful substances present in the blood from entering the retina. Researchers at the Center for ...

Many cases of dementia are characterized by toxic amyloid plaques and tangles in the brain, most notably Alzheimer’s disease. That’s why so many experimental Alzheimer’s drugs target brain plaques.