To obtain electrophysiological recordings in brain slices, sophisticated and expensive pieces of equipment can be used. However, costly microscope equipment with infrared differential interference ...

Manual patch clamping requires considerable skill and experience due to the technically challenging setup requirements, and as such, only allows recording of a small sample of cells (approximately ...

Sutter Instrument is proud to introduce the latest tool for electrophysiology research, the dPatch ® Digital Patch Clamp Amplifier. Using high-speed digital processing, matched with high-resolution ...

Flip-the-Tip Technology Uses Standard Glass Pipettes to Achieve Higher Throughput in Ion Channel Screening The pharmaceutical industry has widely recognized patch clamping as the “gold standard” to ...

Ion channels represent an important class of druggable targets; however, it is generally appreciated in the field that ion-channel targeted drug discovery has been hampered by the unavailability of ...