The field of bone and joint disease research has increasingly focused attention on the multifaceted roles of osteoclasts in both physiological and ...

Activating the GPR133 receptor with a small molecule can rebuild bone from within, offering a new direction for osteoporosis ...

Researchers from Osaka University have identified a gene underlying the development of osteoporosis and developed a new mouse model, pointing the way for future treatments and a greater understanding ...

"In this study, we established an advanced high-resolution microscopy system to visualize extracellular vesicles secreted and captured by mature osteoblasts in vivo and identified a subset of ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts. This ...

A study found mutations that cause SMA may trigger problems with bone cell communication, suggesting a potential new way to treat weak bones.

HERC1 regulates the osteoblastic differentiation. Bone marrow derived MSCs were infected with lentiviral particles carrying either the empty plKO vector as a negative control (plKO) or an shRNA ...

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...

Birmingham researchers have shown PEPITEM, a naturally occurring peptide (small protein) holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct ...

Osteoporosis is characterized by the deterioration of bone tissue, resulting in weak bones that are easily broken. There may be new hope for treating the disease, however, utilizing a naturally ...