When the Human Genome Project published the first draft of the human genome sequence in 2001, many researchers expected to be able to pinpoint protein alterations that would explain the distinctive ...
A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...
Molykutty J. Aryankalayil, Sunita Chopra, Joel Levin, Iris Eke, Adeola Makinde, Shaoli Das, Uma Shankavaram, Claire Vanpouille-Box, Sandra Demaria, C. Norman Coleman ...
Non-coding RNA is a ribonucleic acid molecule that is generated from the non-protein coding DNA sequence, that makes up 98-99% of the human genome. A plethora of different types of functional ...
Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular ...
Researchers have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had ...
Researchers have discovered yet another role for long-noncoding RNAs (lncRNAs): preventing cell suicide in red blood cells. The findings, published today (December 7) in Genes and Development, suggest ...
Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun ...
Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...
A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called P-bodies, providing a ...
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Stress Hormones Mute Brain Genes via RNAs: Study Finds
"These RNAs seem to act like postal codes for gene repression," said Dr. Anuj K. Verma, lead author of the study. "They help direct the polycomb complex to precise chromatin neighborhoods where stress ...
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