GEN

Health Canada Clears DxS’ K-RAS Mutation Kit as Test for Anti-EGFR Therapies

It can assess patients’ suitability for Amgen’s colorectal cancer drug, Vectibix. Canadian regulatory authorities approved DxS’ TheraScreen K-RAS Mutation Kit for use as a diagnostic for anti-EGFR ...
GEN

DxS to Develop K-RAS Mutation Kit as Companion Diagnostic to Erbitux

Company will work with ImClone and BMS to develop FDA-approved test for mCRC patients. DxS is to work with ImClone Systems and Bristol-Myers Squibb on the development of a companion diagnostic for the ...
Medindia

EntroGen Receives FDA Approval for CRCdx® RAS Mutation Detection Kit as Companion Diagnostic for Vectibix®

LOS ANGELES, Oct. 3, 2023 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) has granted approval for EntroGen's CRCdx® RAS Mutation Detection Kit as a companion diagnostic for Vectibix® ...
Business Insider

Invivoscribe Announces FDA Approval for Distribution of the LeukoStrat CDx FLT3 Mutation Assay as an IVD Kit in the United States

SAN DIEGO, May 19, 2020 /PRNewswire/ -- Invivoscribe to offer the LeukoStrat ® CDx FLT3 Mutation Assay as an FDA approved kit with analysis software. In 2017, Invivoscribe's LeukoStrat ® CDx FLT3 ...
Business Wire

GENECAST Launches BRAF Mutation Test Kits with the Highest Detection Sensitivity 0.0001%

Assures 100x upgraded detection sensitivity compare to ddPCR Higher the possibility of precision medicine in the 1st and 2nd stages of cancer patients SEOUL, South Korea--(BUSINESS WIRE)--GENECAST, ...
Nature

A mutation-created novel intra-exonic pre-mRNA splice site causes constitutive activation of KIT in human gastrointestinal stromal tumors

The splicing of nuclear pre-mRNA is a fundamental process for the expression of most metazoan genes. More than half of reported exonic mutations in human disease and cancers are due to ...
Calgary Herald

Researchers at U of C reveal new kit making genetic mutation testing quick, accessible, affordable

Testing for genetic mutations has long been complicated, expensive, time-consuming, and, in some parts of the world, inaccessible. Dr. Pierre Billon, an assistant professor at the University of ...

One overlooked detail in cancer genomes is rewriting which mutations really matter

Correlation does not equal causation. Every cancer cell has genetic mutations, but not all of those mutations necessarily ...
Medical Xpress

Incurable blood cancer tied to gene mutation in new lab model

Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found. Working with ...
Yahoo Finance

Mutation Detection Kits in Genome Editing Market - Competitive Benchmarking and Dashboard Report 2025

Mutation Detection Kits in Genome Editing Market · GlobeNewswire Inc. Dublin, Oct. 14, 2025 (GLOBE NEWSWIRE) -- The "Mutation Detection Kits in Genome Editing Market Report 2025" has been added to ...
Nature

Signal transduction by several KIT juxtamembrane domain mutations

C-kit encodes a receptor tyrosine kinase (RTK) of the same RTK subfamily as the receptors for PDGF, CSF-1 and FLT3 ligand (Rosnet and Birnbaum, 1993). All contain an extracellular ligand-binding ...
Pharmabiz

EntroGen gets US FDA nod for CRCdx RAS mutation detection kit as companion diagnostic for Vectibix

The US Food and Drug Administration (FDA) has granted approval for EntroGen's CRCdx RAS Mutation Detection Kit as a companion diagnostic for Vectibix (panitumumab), a targeted therapy used in the ...