The cytokine family including interleukin-2 and -15 (IL-2 and IL-15) started out in a primitive vertebrate species with three related cytokines IL-2, IL-15, and IL-15-like (IL-15L), all sharing ...

Treatment of rheumatoid arthritis (RA) has evolved from the use of conventional treatments, such as methotrexate, to disease-modifying biologic agents that can slow the disease process and make ...

Expert Rev Resp Med. 2012;6(4):423-429. Some of the anti-inflammatory and immunosuppressive actions derived from corticosteroid therapy may be secondary to augmenting the expression of IL-1RII, a ...

Our immune system consists of many different kinds of protective cells that play a role to fight the infections and diseases. Of these, some cells produce signaling molecules that allow cells all over ...

Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed ...