"By following universal paralogs," says Kaçar, "we can connect the earliest steps of life on Earth to the tools of modern ...

Deep-learning model decodes the regulatory effects of DNA changes ...

Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people ...

IPA, a non-coding RNA from the CUL1 gene that stabilizes the nucleolus and supports ribosome production. Removing it ...

By combining large-scale experiments with deep learning, researchers built a lightweight model that deciphers how regulatory DNA controls gene activity.

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.