Scientists have uncovered a key role for the protein “Frazzled” in building and maintaining the rapid neural connections that allow fruit flies to react in milliseconds.

Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

Twenty-week-old male SHR and WKY rats were used in this study. All protocols were approved by the Institutional Animal Care and Use Committee (IACUC) at the Medical College of Shihezi University and ...

The emergence of gap junctions is a hallmark in the evolution of life from single-cell to multicellular organisms. For the first time, they enabled true social interactions between cells by allowing ...

Neuronal stem cells, originally viewed a source of spare parts that would rebuild damaged circuits, are proving instead to function more like capable paramedics, coming to the rescue of degenerating ...

The heartbeat is controlled by rapid conduction of an electrical current between heart muscle cells. Central to passage of the electrical current are structures known as gap junctions, low resistance ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 7 (Mar. 27, 2001), pp. 4190-4195 (6 pages) Gap junctional communication between microglia was investigated ...

Gap junction protein inhibitor protects mice from death and liver damage after hepatotoxic drug challenge. Inhibiting gap junctions in liver cells could provide a feasible strategy to preventing ...

Ischemia reperfusion injury (IRI) is one of the main cause of organ dysfunction after heart attack and solid organ transplantation, and occurs frequently when the new organ comes from a deceased ...

Researchers studying how a usually benign virus attacks the human heart with sometimes fatal consequences determined that the virus disrupts the heart’s electrical system – and with dual impacts not ...