Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

By fusing enzyme fragments to antibodies, researchers from the Institute of Science Tokyo, in Japan, developed an innovative ...

Slight oscillations lasting just milliseconds have a huge impact on an enzyme's function, according to a new study. Blocking these movements, without changing the enzyme's overall structure or any of ...

UPTON, NY - Scientists have long thought that individual enzymes have specific, single jobs dependent on their molecular shape. According to this premise, enzymes could only evolve to perform new ...

COLLEGE STATION, Nov. 6, 2007 – Fitting a key into a lock may seem like a simple task, but researchers at Texas A&M University are using a method that involves testing thousands of keys to unlock the ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins ...

Throughout evolution, pathogenic microorganisms, such as bacteria, viruses, and fungi, have developed sophisticated defense ...