In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and ...

A newly developed mouse model enables real-time visualization of RNA Polymerase II (RNAP2) during DNA transcription, as ...

Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.

An artificial intelligence model predicts how brain immune cells react to RNA and DNA nanoparticles, helping scientists design safer and more effective nucleic acid therapies faster.

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

Professor Indraneel Mittra and his team show that DNA fragments from dying cells function as agents of horizontal gene transfer in mammalian cells. For decades, scientists have known that bacteria can ...

Big-picture patterns of DNA packaging, gene activation and mutations could hold the information needed to develop a blood-based biopsy for small cell lung cancer patients, according to new work ...

Researchers discovered that bowhead whales achieve extraordinary longevity and cancer resistance through highly efficient and precise DNA repair mechanisms. A whale-specific protein, CIRBP, enhances ...