The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

IT is well established that an increase in the intracellular concentration of ionized calcium after excitation in the membrane is the key factor for initiation of contraction of various types of ...

A new molecular pathway has been identified that is critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. Researchers at UMass Medical ...

IT is believed that muscle contracts or relaxes depending on the concentration of calcium in the sarcoplasm: when the concentration rises to some required level the muscle contracts; when it falls ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Calcium is a key mineral that is known for building strong bones, and teeth. However, beyond its role in the above, this ...

A recent study from Baylor University suggests that high-dose omega‑3 fish oil can improve muscle strength in collegiate ...

Calcium deficiency is a significant health concern, especially for women, as it can lead to complications like osteoporosis, osteopenia, and hypocalcemia. Calcium, essential for bone health, muscle ...

Muscle cramps are involuntarily contracted muscles that do not relax The slight contraction of muscle is spasm A muscle cramp can last for about a fraction of seconds to about an hour One of the major ...