This is a preview. Log in through your library . Abstract We have used light microscopy and serial thin-section electron microscopy to visualize intermediates of chromosome decondensation during G1 ...

In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture ...

The cohesin protein complex is best known for its role in sister chromatid cohesion, which is crucial for accurate chromosome segregation. Mutations in cohesin proteins or their regulators have been ...

In the cell, chromosomal DNA is wrapped around protein complexes in a structure often described as “beads on a string” (Figure 1). Each bead—called a nucleosome—contains roughly 140 base-pairs (bp) of ...

The iconic X-shaped organization of metaphase chromosomes is frequently presented in textbooks and other media. The drawings explain in captivating manner that the majority of genetic information is ...