Our long-term research goal is to decipher the gene regulatory network that directs the embryonic development of various types of neurons in the arcuate nucleus of the hypothalamus (ARC, aka ARH).
Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 25 (June 23, 2020), pp. 14473-14481 (9 pages) Hypothalamic tanycytes are chemosensitive glial cells that ...
PHILADELPHIA-- Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model different brain regions ...
In a new discovery, researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have identified a previously underexplored population of hypothalamic ...
Epigenetic events, such as methylation, during early brain development in mice occur in genomic regions associated with BMI in humans, according to a new study. Once it’s cleaved, the protein ...
Expert Rev Endocrinol Metab. 2008;3(5):577-592. Disclosure: The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial ...
The researchers also discovered that neuropeptide Y (NPY) neurons in the nucleus of the solitary tract (NTS) and ventrolateral medulla (VLM) activate both AMPK-regulated CRH neurons and MC4R neurons ...
Even after eating a large meal, most people can still find room for sweets. Now, research in mice shows that the neurons responsible for feelings of fullness are also those that trigger sugar cravings ...
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