DNA restriction-modification enzymes are enzymes involved in DNA restriction modification. They include DNA restriction endonucleases (restriction enzymes) and their companion modification methylase ...

In the early 1950s, experiments by two teams of researchers, Salvador Luria working with Mary Human and Joe Bertani working with Jean Weigle, showed that some strains of bacteria were more resistant ...

Cellular RNAs are chemically modified by many RNA modification enzymes; however, often the functions of modifications remain unclear, such as for pseudouridine formation in the tRNA TΨC arm by the ...

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene ...

The highly purified restriction endonucleases of E. coli K and coliphage P1 transfer methyl groups from S-adenosylmethionine to adenine residues of unmodified DNA. Incubation of unmodified DNA with ...

Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) and collaborating institutions have developed a DNA-editing method that introduces small chemical modifications at ...